# Molecular Nanoarchitectonic Sensing Layer for Analysis of Volatile Fatty Acids in Bioreactor Headspaces Using a Nanomechanical Sensor https://mdr.nims.go.jp/datasets/0a2c9571-c0f4-44b9-ae3d-2ba65cc6e16e ## File - [Adv Materials Technologies - 2025 - Maji - Molecular Nanoarchitectonic Sensing Layer for Analysis of Volatile Fatty Acids.pdf](https://mdr.nims.go.jp/filesets/1cb9717b-c2e5-4710-a954-2d452e1de05e/download) ([Detail](https://mdr.nims.go.jp/filesets/1cb9717b-c2e5-4710-a954-2d452e1de05e.md)) ## Id 0a2c9571-c0f4-44b9-ae3d-2ba65cc6e16e ## Local identifier ## Visibility open_to_public ## State published ## Created at 2025-10-29T01:32:36.115715Z ## Updated at 2025-10-30T03:30:11.635594Z ## Published at 2025-10-30T03:25:04.555753Z ## Doi ## First published url https://doi.org/10.1002/admt.202500294 ## Date published 2025-05-28 ## Recorded date published 2025-9 ## Resource type journal_article ## Manuscript type vor ## Collection ## Title - title: Molecular Nanoarchitectonic Sensing Layer for Analysis of Volatile Fatty Acids in Bioreactor Headspaces Using a Nanomechanical Sensor title_type: original lang: en ## Description - description: Anerobic digestors have the potential to become a major green energy source in a future sustainable society. To achieve this, effective operational parameters of the reactors must be established and maintained preferably by automation. In situ monitoring and control of anerobic digestor systems is currently a challenging matter based on inconsistent feedstuff composition and the complexity of the biological processes involved, so that reactor shutdowns associated with costly downtime are a common problem. Here we have developed a sensing device for the monitoring of volatile fatty acids, key intermediates during bioreactor operation, in the headspaces of anerobic reactors. The device is compact, contains a sensing element based on a self-assembled molecular layer in conjunction with a nanomechanical sensor, and can be used to monitor volatile fatty acid contents in bioreactors by estimating their relative contents in the reactor headspace in real time. A molecular nanoarchitectonic approach is used to synthesize a microporous polycrystalline sensing layer on a membrane-type surface stress sensor, a nanomechanical sensor. This device allows the close monitoring of volatile fatty acid concentrations in admixture towards cost-effective operation of bioreactors by reducing or eliminating reactor downtime. It represents a simple solution to the problem of real-time reactor monitoring making anerobic digestors a realistic alternative energy source. description_type: abstract lang: und ## Creator - name: Subrata Maji role: author orcid: https://orcid.org/0000-0003-3985-7522 organization: National Institute for Materials Science - name: Jan Hynek role: author orcid: https://orcid.org/0000-0003-1883-9464 - name: Kazushi Nakada role: author - name: Akiko Hori role: author - name: Kosuke Minami role: author orcid: https://orcid.org/0000-0003-4145-1118 organization: National Institute for Materials Science - name: Jan Labuta role: author orcid: https://orcid.org/0000-0002-8329-0634 organization: National Institute for Materials Science - name: Mandeep K. Chahal role: author orcid: https://orcid.org/0000-0002-8810-2196 - name: Daniel T. Payne role: author orcid: https://orcid.org/0000-0001-7707-8381 organization: National Institute for Materials Science - name: Gary J. Richards role: author - name: Lok Kumar Shrestha role: author orcid: https://orcid.org/0000-0003-2680-6291 organization: National Institute for Materials Science - name: Katsuhiko Ariga role: author orcid: https://orcid.org/0000-0002-2445-2955 organization: National Institute for Materials Science - name: Yusuke Yamauchi role: author - name: Genki Yoshikawa role: author orcid: https://orcid.org/0000-0002-9136-8964 organization: National Institute for Materials Science - name: Jonathan P. Hill role: author orcid: https://orcid.org/0000-0002-4229-5842 organization: National Institute for Materials Science ## Contact agent ## Publisher organization: Wiley ## Managing organization ## Keyword - subject: Porphyrin schema: not_defined - subject: MSS Sensor schema: not_defined - subject: Volatile fatty acid sensor schema: not_defined ## Rights - identifier: https://creativecommons.org/licenses/by-nc-nd/4.0/ ## Other identifier(s) ## Data origin - data_origin_type: other ## Embargo ## Journal - title: Advanced Materials Technologies issn: 2365709X volume: '10' issue: '17' article_number: e00294 ## Conference ## Related item ## Funding - identifier: JP20H00392 funder_name: Japan Society for the Promotion of Science - identifier: JP23H05459 funder_name: Japan Society for the Promotion of Science - identifier: JPMJER2003 funder_name: Exploratory Research for Advanced Technology ## Instrument ## Instrument operator ## Instrument managing organization ## Measurement method ## Specimen ## Chemical composition ## Structure for specimen ## Structural feature for specimen ## Specific property for specimen ## Process for specimen treatment ## Computational method ## Energy level/transition state ## Software ## Custom property ## Fileset - id: 1cb9717b-c2e5-4710-a954-2d452e1de05e filename: Adv Materials Technologies - 2025 - Maji - Molecular Nanoarchitectonic Sensing Layer for Analysis of Volatile Fatty Acids.pdf content_type: application/pdf size: 2295527 md5: e25eb5d4dba6deda6c63199b90e9dad2 ## Thumbnail fileset_id: 1cb9717b-c2e5-4710-a954-2d452e1de05e filename: Adv Materials Technologies - 2025 - Maji - Molecular Nanoarchitectonic Sensing Layer for Analysis of Volatile Fatty Acids.pdf